Prism Dry Granulation Line with Roller Compactor (Integrated cGMP Solution)

Prism Dry Granulation Line with Roller Compactor is a fully integrated system designed for efficient, solvent-free, and contamination-free dry granulation of pharmaceutical powders. It is ideal for moisture- and heat-sensitive formulations, ensuring consistent granule quality, improved flow, and excellent compressibility with full cGMP compliance.

Dry granulation is achieved by compacting powder between two counter-rotating rollers to form ribbons, which are milled into uniform granules. This eliminates the need for water, binders, and drying, reducing process time and energy consumption.

* Integrated Equipment Line-up:
- Prism Vacuum / Inline Powder Transfer System for dust-free material transfer
- Prism Roller Compactor for precise densification and ribbon formation
- Inline Pre - Milling / Flake Crusher
- Inline Final Granulator for controlled granule sizing
- Vibro Sifter for uniform particle distribution and fines removal

* Key Features & Advantages:
- Solvent-free process suitable for sensitive formulations
- Closed inline transfer ensuring dust-free and contamination-free operation
- PLC-SCADA automation with recipe control, batch data, and audit trails
- cGMP compliant design with SS 316L contact parts
- Cantilever roller design for easy cleaning and maintenance
- Multiple roller options (plain, knurled, corrugated)
- Precision screw feeder for uniform material flow
- Hydraulic compaction for consistent density
- Minimal fines generation and high yield
- CIP / easy cleaning with quick dismantling
- Complete validation documents (DQ, IQ, OQ, PQ, FAT, SAT)
- Energy-efficient process with no drying stage
- Scalable from R&D to commercial production

* Applications:
- Tablet and capsule manufacturing
- Moisture- and heat-sensitive formulations
- Nutraceutical and herbal products
- Chemical powder processing

Prism Dry Granulation Line delivers a reliable, automated, and compliant solution with high efficiency, reproducibility, and superior product quality.