Liposomal Technology What are liposomes? Tiny, spherical vesicles made of phospholipids. Encapsulates active ingredients. Improves absorption and bioavailability. Protects ingredients from degradation. Can target specific cells or tissues. Used in medicine, nutrition, cosmetics, and vaccines. Challenges include complex production and stability issues. Leading manufacturer of high-quality APIs since 1962. Committed to excellence, we deliver superior APIs meeting stringent WHO-GMP, GMP, ISO, IEC, HACCP, QMC, and FSSAI standards. Our expertise extends to innovative liposomal formulations, ensuring the same exceptional quality and reliability. Trust us for your API needs. Our Liposomal Product Offerings Superior Encapsulation: Maximum active ingredient delivery to target sites. Enhanced Bioavailability: Protected from stomach acids for optimal absorption. Diverse Product Forms: tablets, granules, pellets, suspension and powders to suit your needs. Customized Coatings: We offer a range of coating options to further enhance the performance and stability of your liposomal products. These coatings can help to: – Protect active ingredients from degradation. – Improve solubility and bioavailability. – Control the rate of release. – Target specific tissues or organs.

Liposomal Vitamin B Complex encapsulates the eight water-soluble B vitamins (thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folate, cobalamin) within phospholipid bilayers forming nanoscale vesicles. Prepared via thin-film hydration or ethanol injection, these biocompatible carriers shield against gastrointestinal degradation, enhancing bioavailability through membrane fusion and controlled release for metabolic efficacy. Key Features: • Up to 90% bioavailability vs. 20-30% in standard forms, bypassing gut degradation. • Converts food to ATP, cuts fatigue, aids metabolism. • Supports neurotransmitters, improves mood and cognition. • Promotes red blood cells, oxygen transport, reduces anemia risk. • Targets vegans/elderly, enhances immunity, digestion, vision with stable delivery. Technical & Regulatory Strengths: • All liposomal minerals and vitamins are supported by whitepapers containing complete characterisation data, prepared in accordance with USFDA guidelines. • In vitro study compliance has been established. • The formulations demonstrate the highest encapsulation efficiency. • Three (3) years of stability studies have been performed, confirming long-term product stability.

Liposomal Vitamin C is developed to maximise vitamin C absorption while protecting it from oxidation and gastric degradation. Encapsulation within liposomes enables efficient cellular delivery, allowing higher plasma levels with improved tolerability. This makes it ideal for immune support, antioxidant applications, and high-dose supplementation. Key Features: • Liposomal encapsulation protects Vitamin C from oxidation • Significantly higher bioavailability than conventional ascorbic acid • Reduced gastric irritation at higher doses • Efficient cellular delivery supports immune and antioxidant activity • Stable formulation ensures consistent potency • Multiple absorption benefit compared to non-liposomal Vitamin C Technical & Regulatory Strengths: • All liposomal minerals and vitamins are supported by whitepapers containing complete characterisation data, prepared in accordance with USFDA guidelines. • In vitro study compliance has been established. • The formulations demonstrate the highest encapsulation efficiency. • Three (3) years of stability studies have been performed, confirming long-term product stability.

Liposomal Vitamin D3 encapsulates cholecalciferol, a fat-soluble secosteroid, within phospholipid bilayers, forming unilamellar vesicles via thin-film hydration or ethanol injection. This biomimetic carrier achieves >70% encapsulation efficiency, boosting bioavailability up to 8x through endocytosis and protection from GI degradation, elevating serum levels for calcium regulation and immunomodulation. Key Features: • Up to 8x higher bioavailability via liposomal delivery, maximizing serum levels for efficient nutrient use. • Enhances calcium absorption, strengthening bones and preventing osteoporosis. • Supports immune function, reducing infection risk and inflammation. • Promotes cardiovascular health by regulating blood pressure and clotting. • Improves energy, sleep, physical performance, and mood balance. Technical & Regulatory Strengths: • All liposomal minerals and vitamins are supported by whitepapers containing complete characterisation data, prepared in accordance with USFDA guidelines. • In vitro study compliance has been established. • The formulations demonstrate the highest encapsulation efficiency. • Three (3) years of stability studies have been performed, confirming long-term product stability.

Liposomal vitamin D3 pellets comprise nanoscale phospholipid vesicles encapsulating cholecalciferol within a lipid bilayer matrix, forming stable spherical multiparticulate aggregates for oral delivery. This shields the lipophilic nutrient from gastric acid and enzymatic hydrolysis, promoting intestinal absorption lymphatic transport, yielding 4-6-fold enhanced bioavailability versus conventional forms for optimal calcium regulation and immune modulation. • 4-6x higher absorption via lymphatic routes, shielding cholecalciferol from GI breakdown for peak blood levels. • Enhances calcium/phosphate uptake, boosting density and reducing osteoporosis risk. • Regulates T-cells and antimicrobial peptides for better infection defense. • Supports serotonin synthesis, easing fatigue and seasonal blues. • Sustained release minimizes GI issues, with stable shelf-life potency.

Liposomal vitamin E pellets comprise nanoscale phospholipid vesicles encapsulating tocopherol within a lipid bilayer matrix, forming stable, spherical multiparticulate aggregates for oral administration. This encapsulation shields the antioxidant from oxidative degradation and bile salt interference, promoting lymphatic absorption and yielding 3-5-fold enhanced bioavailability over non-liposomal forms, bolstering cellular protection against lipid peroxidation. • 3-5x higher absorption via lymphatic pathways, protecting tocopherols from GI degradation for optimal cellular delivery. • Shields lipids from peroxidation, reducing oxidative stress in heart, brain, and skin tissues. • Boosts collagen synthesis and UV protection, improving elasticity and reducing inflammation. • Supports T-cell function and cytokine balance for stronger antiviral responses. • Minimizes GI upset with sustained release, ensuring long-shelf-life potency.

Liposomal Vitamin K2 (menaquinone-7, MK-7) encapsulates the fat-soluble cofactor within phospholipid bilayers forming unilamellar vesicles, via thin-film hydration or ethanol injection. This biomimetic delivery shields against enzymatic degradation, boosting intestinal absorption 5-10x over free forms through endocytosis and membrane fusion, enhancing osteocalcin carboxylation for bone and vascular integrity. Key Features: • Liposomal delivery boosts bioavailability up to 5-10x, ensuring more K2 reaches cells for optimal function vs. standard forms. • Activates osteocalcin to direct calcium to bones, reducing osteoporosis risk and supporting density. • Prevents arterial calcification via matrix GLA protein, lowering cardiovascular disease risk. • Aids coagulation and may regulate blood pressure for vascular health. • Enhances with D3 for immunity, muscle function, and overall calcium balance. Technical & Regulatory Strengths: • All liposomal minerals and vitamins are supported by whitepapers containing complete characterisation data, prepared in accordance with USFDA guidelines. • In vitro study compliance has been established. • The formulations demonstrate the highest encapsulation efficiency. • Three (3) years of stability studies have been performed, confirming long-term product stability.

Liposomal Zinc enhances zinc absorption by protecting the mineral through the digestive tract and facilitating efficient cellular delivery. This approach reduces gastric irritation commonly linked with inorganic zinc salts while improving bioavailability. The formulation is well suited for immune support, metabolic health, and long-term nutritional use. Key Features: • Liposomal delivery enhances zinc bioavailability and utilisation • Reduced gastric irritation compared to inorganic zinc salts • Efficient cellular delivery supports immune and metabolic functions • Stable formulation with consistent release profile • Suitable for paediatric, adult, and geriatric nutrition • Multiple absorption advantage over non-liposomal zinc Technical & Regulatory Strengths: • All liposomal minerals and vitamins are supported by whitepapers containing complete characterisation data, prepared in accordance with USFDA guidelines. • In vitro study compliance has been established. • The formulations demonstrate the highest encapsulation efficiency. • Three (3) years of stability studies have been performed, confirming long-term product stability.

Liposomal zinc bisglycinate pellets consist of nanoscale phospholipid vesicles encapsulating bioavailable zinc bisglycinate within a bilayer matrix, forming compact, spherical aggregates for oral delivery. This structure shields zinc from gastric degradation, enhancing intestinal absorption via endocytosis and lymphatic transport, achieving up to 8-fold superior bioavailability compared to conventional form, supporting immune modulation and enzymatic catalysis. • Up to 8-fold higher absorption by protecting zinc from stomach acid, ensuring better systemic delivery. • Reduces GI upset like nausea, thanks to liposomal shielding from gastric acids. • Enhances immune cell function and antiviral defenses via efficient zinc uptake. • Supports metabolic enzymes for quicker vitality gains in 1-2 weeks. • Maintains zinc balance to protect synapses and curb amyloid buildup. • Stable pellets allow precise, sustained-release intake.

Within the range of machines for the manufacture of lipsticks and cocoa bars, Marchesini presents a new ergonomic and versatile solution, the SM300. With the capacity to manufacture up to 300 molds per hour with just one operator, the SM300 is the perfect solution for small laboratories or small production runs. The great versatility of this machine come front the ease of installing new formats, since the technology is based on silicone moulds, easy to change, clean, manufacture and at a very low cost. The main features are: - Complete with 1 single melting tank (5 liters), with volumetric doser at 1 nozzle, fix type - The technological working cycle includes the moulds heating, dosing, cooling up to -20°C by forced air circulation and demoulding - 24 silicone moulds and 1 plastic holder for packaging - The whole operation cycle, semi-automatic type, is controlled by a Siemens PLC

Application The LMQ.C Vertical Sterilizer can sterilize liquids, culture media, glass and metal utensils and sterile waste in CDC,inspection and quarantine institutions, hospital testing departments, university biological laboratories and other medical and biomedical research units.

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Modular HPL panels consist of a polyurethane or rock wool core and compacted, melamine-coated HPL resin panels, 4mm thick on both sides, 48mm thick for partition panels, 3mm thick on both sides, 30mm thick for non-trafficable wall or ceiling cladding panels, and 3mm thick on both sides, 40mm thick for trafficable false ceiling panels. The panels are secured together with anodized aluminum profiles. The aluminum profiles allow for flush assembly between two partition and false ceiling panels, with a 2mm food-grade silicone seal for easy cleaning and disinfection. All anodized or lacquered aluminum profiles have smooth, rounded corners on the inside and outside, making them easy to clean. The smooth surface of the aluminum facilitates cleaning and disinfection. The rounded shape of the anodized aluminum profile avoids Micro Organ retention areas and contributes to the aesthetics of the construction.